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New findings explain why treatment for this arterial occlusive disease often fails to produce the desired results: the problem of vascular disease lies not only in the main arteries of the legs, but also in the smallest blood vessels and surrounding muscle cells.

Trillions of microorganisms in our gut have a significant impact on our health by releasing metabolic products that interact with our body in many ways. Researchers at ETH Zurich and Stanford University have calculated, for the first time, exactly how many of these molecules arrive in our body every day.

A pathway called TNF-Alpha controls the transformation of epithelial cells into aggressive tumor cells. As cancer progresses, the cells activate their own TNF-Alpha program and become invasive. Researchers at the University of Zurich and ETH Zurich believe that this finding could improve the early detection and treatment of skin, esophageal, bladder, and colon cancers.

Long Covid patients suffer from chronic symptoms such as fatigue or shortness of breath. As researchers at the University of Zurich and University Hospital Zurich with support from D-?BSSE data analysts discovered, this is to some extent due to a part of our immune system called the complement system.

Researchers at PSI and ETH Zurich have taken connective tissue cells that have been mechanically reprogrammed to resemble stem cells and transplanted them into damaged skin. In their experiment, they were able to show that this can promote wound healing.